My monthly update on next generation Covid vaccines is online now @PLOS — with a new streamlined structure I hope makes it easier & quicker to read.
News on:
- a major UK grant supporting a UK/US collaboration on a vax from Stanford Uni
- another 4 trials began recruiting in China, Europe, & USA
- another 2 trials are fully recruited in Germany & USA
Plus preclinical reports:
Damn! I'm too old to volunteer.
@hildabast Thank you for continuing to focus on this important topic, and for sharing your expertise!
@hildabast @PLOS Thank you once again! 👏
re SA RNA vaccines: aren't all RNA replicase enzyme error prone ? which means you can start making mRNA with mutations that are toxic ??
@failedLyndonLaRouchite @PLOS No. My explainer: https://absolutelymaybe.plos.org/2024/12/31/self-amplifying-mrna-covid-vaccine-an-introduction/
Susceptible to mRNA fear-mongering, though: https://absolutelymaybe.plos.org/2024/12/28/getting-ready-for-more-mrna-vaccine-fear-mongering-a-compendium/
I am unconvinced that error prone RNA replication enzymes are safe
but I am willing to be guided by data
@hildabast @PLOS
ok, the native RNA replicase appears fairly error prone, but there are hifi versions
https://pmc.ncbi.nlm.nih.gov/articles/PMC3894214/
but it sounds risky to me:
has anyone done a computer model study to ask how many mutations you need to turn the antigen encoded in the sa vaccine into an antigen that might be bad, like an antigen taht gives you MS ?